Added in 2021, the Downtown Pascagoula Historic District contains the following addresses:

• Canty Street: 3006, 3012, 3012 (NC), 3102, 3106, 3108, 3112, 3215, 3217 (NC), 3223-3225
• Convent Avenue: 501, 501A (NC), 503, 600, 601 (NC), 705 (NC), 717 (NC)
• Delmas Avenue: 409, 421 (NC), 502 (NC), 511, 535 (NC), 610-616 (NC), 618-622-630, 617-619, 623, 633 (NC), 634-636, 641, 645, 651, 702 (NC), 703-707, 709 (NC), 710, 711, 718, 720-722, 723, 726 (NC), 733 (NC), 734 (NC)
• Frederic Street: 3204
• Krebs Avenue: 501, 501A (NC), 507, 510, 515 (NC), 517 (NC), 525, 605 (NC), 617, 619, 703-705-707, 709 (NC), 711, 720 (NC)
• Magnolia Street: 3104, 3109 (NC), 3207, 3212 (NC)
• Pascagoula Street: 3010, 3033, 3042, 3103 (NC), 3107-3109, 3109 (NC), 3207, 3255, 3405, 3419
• Watts Avenue: 502, 603, 702-704-706-708 (NC), 707 (NC), 710-712-714 (NC), 716, 720, 727, 729 (NC) 
• Yon Street: 504